ea0063gp65 | Reproductive Axis | ECE2019
Vena Walter
, Pizzocaro Alessandro
, Pelliccione Fiore
, Pivonello Rosario
, Radicioni Antonio
, Selice Riccardo
, Rastrelli Giulia
, Pasquali Daniela
, Calogero Aldo Eugenio
, Ferlin Alberto
, Francavilla Sandro
, Garolla Andrea
, Corona Giovanni
Background: In patients with Klinefelter syndrome (KS) morbidity and mortality seem to be higher than general population, this depending on a wide number of possible comorbidities. Impaired metabolic profile, increased risk of venous thrombosis and the consequent increase of cardiovascular diseases might play a key role in this condition as well as reduced bone mineral density and higher fracture risk. Nowadays testosterone replacement therapy (TRT) is the first-choice treatme...